Potassium Carbonate → HCID 11414044, compound

HRID 2267994Notes

Reaction equation

HRID 2267994 reaction equation
C(=O)([O-])[O-].[K+].[K+].[CH3:7][C:8]([CH3:12])=[CH:9][CH2:10]Br.[CH3:13][C:14]1[C:19](=[S:20])[CH2:18][CH:17]=[CH:16][C:15]=1[C:21]([O:23][CH3:24])=[O:22]>CC(C)=O>[CH3:7][C:8]([CH3:12])=[CH:9][CH2:10][S:20][C:19]1[C:14]([CH3:13])=[C:15]([CH:16]=[CH:17][CH:18]=1)[C:21]([O:23][CH3:24])=[O:22]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 700922-Butene, 1-bromo-3-methyl-HCID 18432362HCID 18432362, compound

Product 1

HCID 11414044HCID 11414044, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

37.9 g (0.275 mol) of potassium carbonate and 43.5 g (0.275 mol) of 3-methyl-2-butenyl bromide were added dropwise to 50 g (0.275 mol) of methyl 3-thio-2-methylbenzoate in 250 ml of acetone, and the mixture was stirred at room temperature for 10 hours. The solvent was distilled off, the residue was taken up in water/ethyl acetate and the organic phase was dried, filtered off and concentrated.

Workup

  1. distillationThe solvent was distilled off
  2. customthe organic phase was dried
  3. filtrationfiltered off
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-a7cbf1037d394906a5bf0b1721d76208
Source dataset
uspto-grants-2001_12
Patent number
US06326333B1

Reaction notes

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