HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyloxonium tetrafluoroborate → 1H-PYRAZOLO[3,4-C]PYRIDINE, 1-CYCLOPENTYL-7-ETHOXY-3-ETHYL-4,5-DIHYDRO-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyloxonium tetrafluoroborate | HCID 2723982 | — |
| Reactant | 1-Cyclopentyl-3-ethyl-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one | HCID 10823542 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1H-PYRAZOLO[3,4-C]PYRIDINE, 1-CYCLOPENTYL-7-ETHOXY-3-ETHYL-4,5-DIHYDRO- | HCID 9845751 | — |
Reaction Steps
esterifying said lactam compound of Formula (9.0.0) using triethyloxonium tetrafluoroborate, (CH3CH2)2OBF4; wherein a reaction mixture is established by slowly adding a solution of triethyloxonium tetrafluoroborate, (CH3CH2)3OBF4 in methylene chloride to a suspension of said lactam compound of Formula (9.0.0) in methylene chloride over a period of 40 minutes; and thereafter, maintaining said reaction mixture at a temperature of from 18° to 22° C., for a period of 21 hours; whereby there is produced a corresponding imino ester (imidate) compound of Formula (10.0.0):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06326495B2 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-4c211279218b471ca5b8a8f55e4ad5b4 |
| Source note | uspto-grants-2001_12 |