Benzyl 4-Hydroxybenzoate → Benzyl 4-[3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)acryloyloxy]-benzoate

HRID 2268206Notes

Reaction equation

HRID 2268206 reaction equation
[OH:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:7])=[CH:4][CH:3]=1.[CH3:18][C:19]1([CH3:36])[CH2:28][CH2:27][C:26]([CH3:30])([CH3:29])[C:25]2[CH:24]=[C:23]([CH:31]=[CH:32][C:33](Cl)=[O:34])[CH:22]=[CH:21][C:20]1=2>>[CH3:18][C:19]1([CH3:36])[CH2:28][CH2:27][C:26]([CH3:29])([CH3:30])[C:25]2[CH:24]=[C:23]([CH:31]=[CH:32][C:33]([O:1][C:2]3[CH:17]=[CH:16][C:5]([C:6]([O:8][CH2:9][C:10]4[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=4)=[O:7])=[CH:4][CH:3]=3)=[O:34])[CH:22]=[CH:21][C:20]1=2

Participants

3

Reactant 2

HCID 7180Benzyl 4-HydroxybenzoateHCID 734315563-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)acryloyl chloride

Product 1

HCID 70215804Benzyl 4-[3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)acryloyloxy]-benzoate

Procedure

In a similar manner to that of Example 1 (d), by reaction of 2.3 g (10 mmol) of benzyl 4-hydroxy-benzoate with 2.8 g (10 mmol) of 3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)acryloyl chloride, 1.7 g (37%) of the expected benzyl ester, with a melting point 97-9° C., are obtained.

Workup

  1. customwith a melting point 97-9° C., are obtained

Sources & evidence

ORD record
ord-e993d2a7ed5d48178029310f3b843c79
Source dataset
uspto-grants-2001_12
Patent number
US06326510B1

Reaction notes

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