HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → HCID 20709190, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 2-(Methylsulfanyl)-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine | HCID 20709189 | — |
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Product | HCID 20709190 | HCID 20709190 | 118.4% |
Reaction Steps
The title compound was prepared by a similar method to preparation 8 from 2-(methylsulfanyl)-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine (16.7 g, 45 mmol) (preparation 42), Oxone (trade mark) (42.0 g, 136 mmol) and solid sodium hydrogen carbonate (20 g, 238 mmol). This gave the title compound (21.4 g) as a white solid. MS: 402 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06326359B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-176d79a468384ac2908b75aeef046f00 |
| Source note | uspto-grants-2001_12 |