反应详情

A solution of [2-(3-chloro-5-{isopropyl-[2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamoyl}phenoxy)-ethyl]-pyridin-4-yl-carbamic acid tert-butyl ester (0.028 g) in a mixture of dichtoromethane (0.5 ml) and trifluoroacetic acid (1 ml) was stored at room temperature for 2 h and then concentrated under reduced pressure. The residue was subjected to preparative hplc and the title compound (0.023 g) was obtained as a colourless gum by concentration of the required fraction under reduced pressure and drying by repetitive addition of acetonitrile and concentration under reduced pressure.

1. concentrationconcentrated under reduced pressure