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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2268668Generated: October 30, 2026

Trifluoroacetic acid → HCID 18348945, compound

https://huagongshe.com/reaction/2268668

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 54289105HCID 54289105—
SolventDichloromethaneHCID 6344—
ProductHCID 18348945HCID 18348945—

Reaction Steps

A solution of [2-(3-{[2-(3-amino[1,2,4]oxadiazol-5-yl)-ethyl]-isopropyl-carbamoyl}-5-chloro-phenoxy)-ethyl]-pyridin-4-yl-carbamic acid tert-butyl ester (0.064 g) in dichloromethane (1 ml) and trifluoroacetic acid (1 ml) was stored at room temperature for 5 h and then concentrated under reduced pressure. The residue was subjected to preparative hplc to give the title compound as a pale yellow foam (0.043 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06326386B1
Source datasetuspto-grants-2001_12
ORD IDord-e62ceb4e9d774e5d966a645f8b0c9749
Source noteuspto-grants-2001_12