反应详情

温度

22.5 °C

1.2 g of trimethoxymethane and 8.7 ml of 25% strength by weight ethanolic HCl solution were added to 14.8 g of 1-phenylpropane-1,2-dione dissolved in 27.5 ml of methanol. The reaction mixture was stirred at 20 to 25° C. for 2 hours, and the solvent was then removed by distillation. The residue was taken up in methyl tert-butyl ether (MTBE) and the solution was washed with water. The organic phases were dried and the solvent removed by distillation. 18.2 g of product were obtained as a clear oil.

1. customthe solvent was then removed by distillation
2. washthe solution was washed with water
3. customThe organic phases were dried
4. customthe solvent removed by distillation