Methanol → HCID 178483059, compound

Participants

Reaction Steps

6-Amino-9-benzyl-2-dimethylamino-8-bromopurine (51 mg, 0.15 mmol) in concentrated hydrochloric acid (30 ml) and methanol (10 ml) were refluxed for 5 hours under heating. After removal of methanol, the reaction mixture was made basic with 28% aqueous ammonia. The resulting crystals were filtered, washed with water and dried to give the subject compound (38 mg, yield 91%).

Provenance & Evidence