Hydrochloric Acid → HCID 178509055, compound

Participants

Reaction Steps

To a methanol solution (5 ml) containing 500 mg of sodium hydroxide was added 6-amino-9-benzyl-8-hydroxy-2-(methoxycarbonylmethyl)thiopurine (64 mg, 0.19 mmol). The solution was refluxed under heating, neutralized with 2N hydrochloric acid, filtered and washed with water to give the subject compound (32 mg, yield 52%).

Provenance & Evidence