Ammonia methanol → HCID 178514053, compound

Participants

Reaction Steps

A 28% ammonia/methanol solution was added to 6-amino-9-benzyl-8-hydroxy-2-(methoxycarbonylmethyl)thiopurine (75 mg, 0.22 mmol). The solution was heated in autoclave for 6 hours and then the solvent was removed in vacuo. To the residue was added methanol and the resulting crystals were filtered to give the subject compound (64 mg, yield 89%).

Provenance & Evidence