HCID 18332748, compound → HCID 178496194, compound

Participants

Reaction Steps

6-Amino-9-(4-fluorobenzyl)-8-methoxy-2-(2-methoxyethoxy)purine (49 mg, 0.14 mmol) in concentrated hydrochloric acid (20 ml) was stirred for 12 hours. The reaction mixture was evaporated in vacuo to dryness and then 28% aqueous ammonia was added thereto. The resulting crystals were filtered to give the subject compound (36 mg, yield 77%).

Provenance & Evidence