HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 178508977, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 6-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurine | HCID 18332790 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178508977 | HCID 178508977 | 51% |
Reaction Steps
6-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurine (83 mg, 0.25 mmol) in concentrated hydrochloric acid (5 ml) was stirred at room temperature for 4 hours. The reaction mixture was neutralized with 28% aqueous ammonia and the resulting crystals were filtered and washed with water to give the subject compound (40 mg, yield 51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329381B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-c3f16079a0c445ff8e00430a4c89f364 |
| Source note | uspto-grants-2001_12 |