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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269068Generated: October 30, 2026

Ammonia → HCID 178508977, compound

https://huagongshe.com/reaction/2269068

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant6-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurineHCID 18332790—
SolventHydrochloric AcidHCID 313—
ProductHCID 178508977HCID 17850897751%

Reaction Steps

6-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurine (83 mg, 0.25 mmol) in concentrated hydrochloric acid (5 ml) was stirred at room temperature for 4 hours. The reaction mixture was neutralized with 28% aqueous ammonia and the resulting crystals were filtered and washed with water to give the subject compound (40 mg, yield 51%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329381B1
Source datasetuspto-grants-2001_12
ORD IDord-c3f16079a0c445ff8e00430a4c89f364
Source noteuspto-grants-2001_12