反应详情

温度

20 °C

A quantity of 3.7 g of 3-hydroxy-2,4-difluoro-bromobenzene is dissolved in 25 ml of acetone and 2.5 g of potassium carbonate is added followed by 2.2 ml of methyl iodide. The mixture is stirred at 20° C. for 6 hours and the solvent evaporated. After addition of dichloromethane, the suspension is filtered. Evaporation of the solvent affords the desired product.

1. customthe solvent evaporated
2. additionAfter addition of dichloromethane
3. filtrationthe suspension is filtered
4. customEvaporation of the solvent