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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269272Generated: October 31, 2026

(2S, 3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine → (2S,3S)-3-[(5-Methoxy-1-(trifluoromethyl)indan-6-yl)methylamino]-2-phenylpiperidine

https://huagongshe.com/reaction/2269272

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S, 3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidineHCID 57090611—
Reactant(2S, 3S)-1-tert-Butoxycarbonyl-3-[(5-methoxy-1-(trifluoromethyl)indan-6-yl)methylamino]-2-phenylpiperidineHCID 70008982—
Product(2S,3S)-3-[(5-Methoxy-1-(trifluoromethyl)indan-6-yl)methylamino]-2-phenylpiperidineHCID 44593633—

Reaction Steps

This Compound was prepared from Compound 66 in the same manner of Compound 27.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329396B1
Source datasetuspto-grants-2001_12
ORD IDord-f88657638da64eb7ac9fe100e7299e0c
Source noteuspto-grants-2001_12