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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269288Generated: October 30, 2026

(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-((2,2-difluoro-6-methoxy-1,2,3,4-tetrahydronaphthalen-7-yl)methyl)amino-2-phenylpiperidine

https://huagongshe.com/reaction/2269288

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidineHCID 11311934—
Reactant(2S, 3S)-1-tert-Butoxycarbonyl-2-phenyl-3-(5-(2,2,2-trifluoro-1-(trifluoromethyl)ethyl)-2-methoxybenzyl)aminopiperidineHCID 15549735—
Product(2S,3S)-1-tert-Butoxycarbonyl-3-((2,2-difluoro-6-methoxy-1,2,3,4-tetrahydronaphthalen-7-yl)methyl)amino-2-phenylpiperidineHCID 70001230—

Reaction Steps

This compound was prepared from Compound 96 and Compound 12 in the same manner of Compound 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329396B1
Source datasetuspto-grants-2001_12
ORD IDord-1242df3ac8c443949b04588fd0eb4088
Source noteuspto-grants-2001_12