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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269323Generated: November 1, 2026

HCID 53961705, compound → HCID 18179531, compound

https://huagongshe.com/reaction/2269323

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53961705HCID 53961705—
SolventTrifluoroacetic acid methylene chlorideHCID 21863450—
ProductHCID 18179531HCID 18179531—

Reaction Steps

A solution of 1-[4-(4-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid tert-butyl ester in 2 mL of 1:1 trifluoroacetic acid-CH2Cl2 was stirred for 15 min-2 h at room temperature. Concentration in vacuo afforded 1-[4-(4-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid as a colorless syrup:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329397B1
Source datasetuspto-grants-2001_12
ORD IDord-2086a5cabf4f4f6eb1f5555c90d67187
Source noteuspto-grants-2001_12