Sodium borohydride → HCID 18347065, compound

HRID 2269381Notes

Reaction equation

HRID 2269381 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([C:26]2[CH:31]=[CH:30][CH:29]=[C:28]([N+:32]([O-])=O)[CH:27]=2)[NH:10][CH2:11][CH2:12][CH:13]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:5][CH:4]=1.[BH4-].[Na+]>C(O)C.O.O.O.O.O.O.[Ni](Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]([NH:10][CH2:11][CH2:12][CH:13]([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[C:26]2[CH:27]=[C:28]([NH2:32])[CH:29]=[CH:30][CH:31]=2)=[CH:7][CH:8]=1

Participants

5

Reactant 2

HCID 4311764Sodium borohydrideHCID 18347140HCID 18347140, compound

Product 1

HCID 18347065HCID 18347065, compoundYield 81%

Reagents, catalysts & solvents 2

HCID 11791229Dichloronickel;hexahydrateCatalystHCID 702EthanolSolvent

Procedure

In a similar manner to that described in Example (1b), a solution of N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]-N-(3,3-diphenylpropyl)amine (3.53 g) [prepared as described in step (a) above] in ethanol (70 ml), nickel chloride hexahydrate (3.71 g) and sodium borohydride (1.18 g) were reacted, to afford the title compound (2.67 g) as a yellow oil.

Sources & evidence

ORD record
ord-e930b556bc5b40dba8e7f3313d2b4214
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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