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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269388Generated: October 30, 2026

Sodium borohydride → HCID 18347070, compound

https://huagongshe.com/reaction/2269388

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 18334177HCID 18334177—
CatalystDichloronickel;hexahydrateHCID 11791229—
SolventEthanolHCID 702—
ProductHCID 18347070HCID 1834707085.6%

Reaction Steps

In a similar manner to that described in Example (1b), a solution of N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]-N-[1-(2-thienyl)ethyl]amine (2.11 g) [prepared as described in step (a) above] in ethanol (40 ml), nickel chloride hexahydrate (2.71 g) and sodium borohydride (863 mg) were reacted, to afford the title compound (1.66 g) as a dark brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329405B1
Source datasetuspto-grants-2001_12
ORD IDord-8fb7296a40a947b89f4929f94a5ac5a0
Source noteuspto-grants-2001_12