HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 70189155, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 70189173 | HCID 70189173 | — |
| Catalyst | Dichloronickel;hexahydrate | HCID 11791229 | — |
| Product | HCID 70189155 | HCID 70189155 | 94.6% |
Reaction Steps
In a similar manner to that described in Example (1b), isomer A of N-[(4-methoxy-3-nitrophenyl)-(4-fluorophenyl)methyl]-N-[(S)-1-phenylethyl]amine (670 mg) [prepared as described in step (a) above], nickel chloride hexahydrate (856 mg) and sodium borohydride (272 mg) were reacted, to afford isomer A (584 mg) of the title compound as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329405B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-c7ae2f13fc844e33a87495d87719e21f |
| Source note | uspto-grants-2001_12 |