Sodium borohydride → HCID 70189156, compound

Participants

Reaction Steps

In a similar manner to that described in Example (15b), N-[(3,4-dimethoxy-5-nitrophenyl)-(4-fluorophenyl)methyl]-N-[(S)-1-phenylethyl]amine (2.73 g) [prepared as described in step (a) above], nickel chloride hexahydrate (3.19 g) and sodium borohydride (1.01 g) were reacted, and the reaction mixture was purified, to afford isomer A (895 mg) as a yellow oil and isomer B (319 mg) as a pale yellow oil of the title compound.

Provenance & Evidence