反应详情

In a similar manner to that described in Example (25a), cyclohexyl-3-nitrophenylketone (3.0 g), 1-(3,4-difluorophenyl)ethylamine hydrochloride (4.98 g) triethylamine (10.8 ml), titanium tetrachloride (1.70 ml), nickel chloride hexahydrate (6.11 g), and sodium borohydride (2.05 g) were reacted, to afford the title compound (1.59 g) as a yellow oil.

1. customwere reacted