3-Cyclobutene-1,2-dione, 3,4-dimethoxy- → HCID 18347092, compound

HRID 2269418Notes

Reaction equation

HRID 2269418 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:23]=[CH:24][CH:25]=1)[CH2:5][NH:6][CH:7]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)[C:8]1[CH:9]=[C:10]([NH2:14])[CH:11]=[CH:12][CH:13]=1.[CH3:26][O:27][C:28]1[C:29](=O)[C:30](=[O:34])[C:31]=1[O:32]C>>[F:1][C:2]1[CH:3]=[C:4]([CH:23]=[CH:24][CH:25]=1)[CH2:5][NH:6][CH:7]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)[C:8]1[CH:9]=[C:10]([NH:14][C:29]2[C:30](=[O:34])[C:31](=[O:32])[C:28]=2[O:27][CH3:26])[CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 1232273-Cyclobutene-1,2-dione, 3,4-dimethoxy-HCID 18334165HCID 18334165, compound

Product 1

HCID 18347092HCID 18347092, compoundYield 90.3%

Procedure

In a similar manner to that described in Example (1c), 3-[(3-fluorobenzyl amino)-(4-methoxyphenyl)methyl]phenylamine (409 mg) [prepared as described in step (b) above] and 3,4-dimethoxy-3-cyclobutene-1,2-dione (173 mg) were reacted, to afford the title compound (490 mg) as a pale yellow oil.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-8e3a79bc8ab440bcb56398209bf287d2
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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