HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18334129, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | Benzenemethanamine, 3,4-difluoro-α-methyl-, hydrochloride (1:1) | HCID 18347113 | — |
| Reactant | 2-Methoxy-5-nitrophenyl 4-methoxyphenyl ketone | HCID 70188099 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 18334129 | HCID 18334129 | — |
Reaction Steps
Following a similar procedure to that described in Example (1a), 2.02 of 2-methoxy-5-nitrophenyl 4-methoxyphenyl ketone, 2.02 a of 1-(3,4-difluorophenyl)ethylamine hydrochloride, 4,37 ml of triethylamine, 0.69 ml of titanium tetrachloride, 1.46 g of sodium cyanoborohydride and 0.45 ml of acetic acid were reacted, to obtain 2.10 g of the title compound as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329405B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-779bf44652df4982a8a90c8e2fdc9b1d |
| Source note | uspto-grants-2001_12 |