反应详情

Following a reaction and purification procedure similar to those described in Example (59b), 4.40 g of N-[(R)-1-(3,5-difluorophenyl)ethyl]-N-[(4-fluorophenyl)-(3-nitrophenyl)methyl]amine [prepared as described in step (a) above], 6.54 g of nickel chloride hexahydrate and 1.81 g of sodium borohydride were reacted, to obtain 1.24 g of isomer A and 1.66 g of isomer B of the title compound as yellow oils, respectively.

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