HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 70188103, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 70189747 | HCID 70189747 | — |
| Catalyst | Dichloronickel;hexahydrate | HCID 11791229 | — |
| Product | HCID 70188103 | HCID 70188103 | — |
Reaction Steps
Following a reaction and purification procedure similar to those described in Example (59b), 2.70 g of N-[(4-fluorophenyl)-(3-nitrophenyl)methyl]-N-[(R)-1-phenylpropyl]amine [prepared as described in step (a) above], 4.06 g of nickel chloride hexahydrate and 1.18 g of sodium borohydride were reacted, to obtain 778 mg of isomer A and 615 mg of isomer B of the title compound as yellow oils, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329405B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-47009814611e40a4b79d7f6480ff141a |
| Source note | uspto-grants-2001_12 |