Sodium borohydride → HCID 18334178, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 2.41 of N-[(4-fluorophenyl)-(3-nitrophenyl)methyl]-N-[1-(thiophen-2-yl)ethyl]amine [prepared as described in step (a) above], 3.22 g of nickel chloride hexahydrate and 1.03 g of sodium borohydride were reacted, to obtain 687 mg of isomer A and 552 mg of isomer B of the title compound as pale yellow oils, respectively.

Provenance & Evidence