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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269481Generated: October 30, 2026

(4-Methoxyphenyl)(3-nitrophenyl)methanone → N-[(R)-1-(3-Fluorophenyl)ethyl]-N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]amine

https://huagongshe.com/reaction/2269481

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Methoxyphenyl)(3-nitrophenyl)methanoneHCID 794540—
Reactant(R)-1-(3-Fluorophenyl)ethylamine hydrochlorideHCID 45072322—
ProductN-[(R)-1-(3-Fluorophenyl)ethyl]-N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]amineHCID 70188098—

Reaction Steps

Following a similar procedure to that described in Example (1a), 11.16 g of 4-methoxyphenyl 3-nitrophenyl ketone and 7.62 g of (R)-1-(3-fluorophenyl)ethylamine hydrochloride were reacted, to obtain 15.11 of the title compound as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329405B1
Source datasetuspto-grants-2001_12
ORD IDord-889f2c59ffc74cd58d24c3bcbf0b55ac
Source noteuspto-grants-2001_12