Sodium borohydride → HCID 70189348, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 3.74 g of N-[1-(3,4-difluorophenyl)ethyl]-N-[(4-methylthiophenyl)-(3-nitrophenyl)methyl]amine [prepared as described in step (a) above], 4.29 g of nickel chloride lhexahydrate, 1.37 g of sodium borohydride and 80 ml of methanol were reacted, to obtain 796 mg of isomer A and 400 mg of isomer B of the title compound as colorless oils, respectively.

Provenance & Evidence