3-Cyclobutene-1,2-dione, 3-(1,1-dimethylethoxy)-4-methoxy- → HCID 86757668, compound

HRID 2269499Notes

Reaction equation

HRID 2269499 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([NH:17][C:18]([CH3:26])([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH3:19])[C:10]2[CH:11]=[C:12]([NH2:16])[CH:13]=[CH:14][CH:15]=2)=[CH:5][CH:4]=1.[C:27]([O:31][C:32]1[C:33](=O)[C:34](=[O:38])[C:35]=1[O:36]C)([CH3:30])([CH3:29])[CH3:28]>CO>[C:27]([O:31][C:32]1[C:35](=[O:36])[C:34](=[O:38])[C:33]=1[NH:16][C:12]1[CH:13]=[CH:14][CH:15]=[C:10]([CH:9]([C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[NH:17][C:18]([CH3:26])([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH3:19])[CH:11]=1)([CH3:30])([CH3:28])[CH3:29]

Participants

4

Reactant 2

HCID 105593803-Cyclobutene-1,2-dione, 3-(1,1-dimethylethoxy)-4-methoxy-HCID 70189115HCID 70189115, compound

Product 1

HCID 86757668HCID 86757668, compoundYield 82.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following a similar procedure to that described in Example (94c), 1.19 g of 3-[(4-methoxyphenyl)-(1-methyl-1-phenylethylamino)methyl]phenylamine [prepared as described in step (b) above], 886 mg of 3-t-butoxy-4-methoxy-3-cyclobutene-1,2-dione and 40 ml of methanol were reacted, to obtain 1.42 g of the title compound as a white foamy solid.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3de26452f0584ba89cdbc833e3416eae
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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