Sodium borohydride → HCID 70188092, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 7.60 g of N-[(R)-1-(4-fluorophenyl)ethyl]-N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]amine [prepared as described in step (a) above], 9.51 g of nickel chloride hexahydrate and 3.03 g of sodium borohydride were reacted, to obtain 1.52 g of isomer A and 1.39 g of isomer B of the title compound, each as a pale yellow oil.

Provenance & Evidence