Sodium borohydride → HCID 70188151, compound

Participants

Reaction Steps

Following a similar reaction, separation and purification procedure to that described in Example (59b), 5.88 g of N-[(R)-1-(3 4-difluorophenyl)ethyl]-N-[(3-nitrophenyl)-(p-tolyl)methyl]amine [prepared as described in step (a) above], 7.31 g of nickel chloride hexahydrate and 2.33 g of sodium borohydride were reacted, to obtain 0.91 g of isomer A and 335 mg of isomer B of the title compound, each as a colorless oil.

Provenance & Evidence