Tin tetrachloride → HCID 70188110, compound

HRID 2269515Notes

Reaction equation

HRID 2269515 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C@H:9]([NH:11][CH:12]([C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([N+:19]([O-])=O)[CH:14]=2)[CH3:10])[CH:6]=[CH:7][CH:8]=1.[Sn](Cl)(Cl)(Cl)Cl>C(O)C>[CH3:29][O:28][C:25]1[CH:26]=[CH:27][C:22]([CH:12]([NH:11][C@@H:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH3:10])[C:13]2[CH:14]=[C:15]([NH2:19])[CH:16]=[CH:17][CH:18]=2)=[CH:23][CH:24]=1

Participants

4

Reactant 2

HCID 24287Tin tetrachlorideHCID 70189227HCID 70189227, compound

Product 1

HCID 70188110HCID 70188110, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a similar reaction, separation and purification procedure to that described in Example (94b), 9.04 g of N-[(R)-1-(3-methoxyphenyl)ethyl]-N-[(4-methoxyphenyl)-(3-nitrophenyl)methyl]amine [prepared as described in step (a) above], 17.5 g of anhydrous tin chloride and 150 ml of ethanol were reacted, to obtain 1.48 g of isomer A and 1.28 g of isomer B of the title compound as a pale yellow oil.

Workup

  1. customa similar reaction, separation and purification procedure to
  2. customwere reacted

Sources & evidence

ORD record
ord-feaf77188428465a9ede8bd0bea0faf8
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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