HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 70189280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 70189226 | HCID 70189226 | — |
| Catalyst | Dichloronickel;hexahydrate | HCID 11791229 | — |
| Product | HCID 70189280 | HCID 70189280 | — |
Reaction Steps
Following a procedure similar to that described in Example (59b), 3.59 g of N-[(p-tolyl)-(3-nitrophenyl)methyl]-N-[(R)-1-(3-fluorophenyl)ethyl]amine [prepared as described in step (a) above], 4.68 g of nickel chloride hexahydrate and 1.49 g of sodium borohydride were reacted, separated and purified, to obtain 955 mg of isomer A and 649 mg of isomer B of the title compound, each as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06329405B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-3278df609954476c9c2b9698c125b3e6 |
| Source note | uspto-grants-2001_12 |