HRID2269521

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：C[C@@H](NC(c1ccccc1)c1cccc([N+](=O)[O-])c1)c1cccc(F)c1

HCID70189344

未命名化合物

PRODUCTS

生成物

结构：C[C@@H](NC(c1ccccc1)c1cccc(N)c1)c1cccc(F)c1

HCID70188111

未命名化合物

收率 92.6%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID11791229

Nickel(II) chloride hexahydrate

H12Cl2NiO6

PROCEDURE

实验过程

Following a procedure similar to that described in Example (1b), 1.37 g of N-[phenyl-(3-nitrophenyl)methyl]-N-[(R)-1-(3-fluorophenyl)ethyl)amine [prepared as described in step (a) above], 2.14 g of nickel chloride hexahydrate and 623 mg of sodium borohydride were reacted, to obtain 1.16 g of the title compound as a yellow oil.

WORKUP

后处理

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