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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2269523Generated: November 2, 2026

Sodium → HCID 70189343, compound

https://huagongshe.com/reaction/2269523

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodiumHCID 5360545—
ReactantHCID 70188140HCID 70188140—
CatalystDichloronickel;hexahydrateHCID 11791229—
ProductHCID 70189343HCID 7018934389.6%

Reaction Steps

Following a procedure similar to that described in Example (1b), 5.38 g of N-[(4-fluorophenyl)-(3-nitrophenyl)methyl]-N-[(R)-1-(napthalen-1-yl)ethyl]amine [prepared as described in step (a) above], 6.39 g of nickel chloride hexahydrate and 2.03 g of sodium bobohydride were reacted and purified, to obtain 4.46 g of the title compound as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06329405B1
Source datasetuspto-grants-2001_12
ORD IDord-3b66c67962d4451c9fb361d55cc8d20c
Source noteuspto-grants-2001_12