反应详情

Cool the 1-(t-butoxycarbonyl)-4-(1-(4-fluoro-benzyl)-1H-benzoimidazole-2-carbonyl)-piperidine in an ice bath. Add trifluoroacetic acid and mix. After 15 minutes, add diethyl ether. Collect the residue by filtration and dried under vacuum. Recrystallize from ethanol/ether and dry resulting solid under vacuum to give the title compound.

1. customCollect the residue
2. filtrationby filtration
3. customdried under vacuum
4. customRecrystallize from ethanol/ether
5. customdry
6. customresulting solid under vacuum