HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → 2-[(5,6-Dimethyl-pyridin-2-ylamino)-methylene]-malonic acid diethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 6-Amino-2,3-dimethylpyridine | HCID 262484 | — |
| Product | 2-[(5,6-Dimethyl-pyridin-2-ylamino)-methylene]-malonic acid diethyl ester | HCID 57754778 | 88.7% |
Reaction Steps
Experimental conditions analogous to those described for Step 1 of Example 60 were used with 5 g (40.93 mmol) of 5,6-Dimethyl-pyridin-2-ylamine and 8.2 mL (40.93 mmol) of 2-ethoxymethylene malonic acid diethyl ester to afford 10.61 g of 2-[(5,6-Dimethyl-pyridin-2-ylamino)-methylene]-malonic acid diethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-8f66f8a7967c448f9564b0f6b850869b |
| Source note | uspto-grants-2009_07 |