HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Sodium 6,8-dihydroxyoctanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 6,8-Dihydroxyoctanoic acid methyl ester | HCID 11355960 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Sodium 6,8-dihydroxyoctanoate | HCID 23714776 | — |
Reaction Steps
Methyl 6,8-dihydroxyoctanoate (0.15 g, 0.80 mmol; containing about 10% of the 6,7-isomer) was dissolved in 3 mL of methanol and 1.00 M sodium hydroxide in methanol (0.80 mL, 0.80 mmol) was added. The solution was stirred under reflux for 3 hr. The solvent was evaporated in vacuo yielding 0.15 g of sodium 6,8-dihydroxyoctanoate as a white powder. Yield was quantitative.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331559B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-48a55d2b2b2143169c415ce09cccbe75 |
| Source note | uspto-grants-2001_12 |