HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphenyl Ether → 3-(3-Fluoro-4-methoxy-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphenyl Ether | HCID 7583 | — |
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | 3-Ethoxy-2-(3-fluoro-4-methoxy-benzoyl)acrylic acid methyl ester | HCID 66879749 | — |
| Product | 3-(3-Fluoro-4-methoxy-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one | HCID 57754627 | — |
Reaction Steps
Experimental conditions analogous to those described for Step 1 of Example 1 were used with 0.70 g (2.61 mmol) of 3-Ethoxy-2-(3-fluoro-4-methoxy-benzoyl)acrylic acid methyl ester, 0.25 g (2.61 mmol) of 3-aminopyridine, and 15 mL of diphenyl ether to yield 3-(3-Fluoro-4-methoxy-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-65b06b8321f947f7bc0c6e336ed63eef |
| Source note | uspto-grants-2009_07 |