反应详情

Experimental conditions analogous to those described for Step 1 of Example 1 were used with 0.70 g (2.61 mmol) of 3-Ethoxy-2-(3-fluoro-4-methoxy-benzoyl)acrylic acid methyl ester, 0.25 g (2.61 mmol) of 3-aminopyridine, and 15 mL of diphenyl ether to yield 3-(3-Fluoro-4-methoxy-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one.