HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 22632876, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 6951153 | HCID 6951153 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 22632876 | HCID 22632876 | 92.3% |
Reaction Steps
Following the procedure of Example C-2, the reaction of 2,6-dichloro-5-fluoro-3-pyridinecarboxylate (2.00 g, 8.4 mmol) with 4-methylpiperazine (0.95 mL, 8.4 mmol) in acetonitrile (10 mL) in the presence of triethylamine (1.75 mL, 12.58 mmol) gave 2.34 g of the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331538B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-61bd12aa9aff4270aceb7f0d5861ba92 |
| Source note | uspto-grants-2001_12 |