HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22632963, compound → HCID 22633000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22632963 | HCID 22632963 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 22633000 | HCID 22633000 | 83.2% |
Reaction Steps
Using the General Method 6A, the reaction of 10% Pd/C (0.04 g) with 1-(3-methoxyphenyl)-6-fluoro-3-benzyloxy-7-(4-methylpiperazin-1-yl)-1H-quinazoline-2,4-dione (Example U-1, 0.12 g, 0.24 mmol) afforded 0.08 g of the title compound as a solid, mp 158-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331538B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-90c58944b79c452fb565ec4b1e872ebe |
| Source note | uspto-grants-2001_12 |