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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270280Generated: October 30, 2026

HCID 22632963, compound → HCID 22633000, compound

https://huagongshe.com/reaction/2270280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22632963HCID 22632963—
CatalystPalladiumHCID 23938—
ProductHCID 22633000HCID 2263300083.2%

Reaction Steps

Using the General Method 6A, the reaction of 10% Pd/C (0.04 g) with 1-(3-methoxyphenyl)-6-fluoro-3-benzyloxy-7-(4-methylpiperazin-1-yl)-1H-quinazoline-2,4-dione (Example U-1, 0.12 g, 0.24 mmol) afforded 0.08 g of the title compound as a solid, mp 158-160° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331538B1
Source datasetuspto-grants-2001_12
ORD IDord-90c58944b79c452fb565ec4b1e872ebe
Source noteuspto-grants-2001_12