HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22632900, compound → HCID 22632928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22632900 | HCID 22632900 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 22632928 | HCID 22632928 | 65.9% |
Reaction Steps
Using the General Method 6A, the reaction of 10% Pd/C (0.07 g) with 1-(3-fluorophenyl)-6-fluoro-3-benzyloxy-7-(4-methylpiperazin-1-yl)-1H-quinazoline-2,4-dione (Example Z-1, 0.209 g, 0.43 mmol) provided 0.11 g of the title compound as a solid, mp 176-178° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331538B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-3630708268ed44bf8585e85c51e51b07 |
| Source note | uspto-grants-2001_12 |