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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270299Generated: October 30, 2026

HCID 22632931, compound → HCID 22633041, compound

https://huagongshe.com/reaction/2270299

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22632931HCID 22632931—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22633041HCID 2263304148.1%

Reaction Steps

Using the method of Example 56, 20% Pd/C (40 mg), 3-benzyloxy-1-(2,4-difluorophenyl)-6-fluoro-7-pyrrolidin-1-yl-1H-pyrido[2,3-d]pyrimidine-2,4-dione (Example Q4, 0.15 g, 0.33 mmol) were combined in 50 mL of THF, to give 0.06 g of the title compound as a solid, mp 189-191° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331538B1
Source datasetuspto-grants-2001_12
ORD IDord-485dc98ffa2844b2a1ed572b79448532
Source noteuspto-grants-2001_12