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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270301Generated: October 31, 2026

HCID 22632999, compound → HCID 22633025, compound

https://huagongshe.com/reaction/2270301

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22632999HCID 22632999—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22633025HCID 2263302557.3%

Reaction Steps

Using the method of Example 56, 20% Pd/C (25 mg), 3-benzyloxy-6-fluoro-7-pyrrolidin-1-yl-1-(3-trifluoromethylphenyl)-1H-pyrido[2,3-d]pyrimidine-2,4-dione (Example S-4, 0.17 g, 0.34 mmol) were combined in 25 mL of THF, to give 0.08 g of the title compound as a solid, mp 136-138° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331538B1
Source datasetuspto-grants-2001_12
ORD IDord-95e6b8c337ee424e9e33fa22535c50c3
Source noteuspto-grants-2001_12