Diethanolamine → HCID 5184352, compound

HRID 2270363Notes

Reaction equation

[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[CH3:8][O:9][C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][CH:17]=1)[CH2:13]Cl>>[OH:4][CH2:3][CH2:2][N:1]([CH2:13][C:12]1[CH:15]=[CH:16][CH:17]=[C:10]([O:9][CH3:8])[CH:11]=1)[CH2:5][CH2:6][OH:7]

Participants

Reactant 2

HCID 8113Diethanolamine

HCID 699943-Methoxybenzyl chloride

Product 1

HCID 5184352HCID 5184352, compound

Procedure

2-[(2-Hydroxy-ethyl)-(3-methoxy-benzyl)-amino]-ethanol was prepared according to the general method as outlined in example 83. Starting from diethanolamine (3.1 g, 29.5 mmol) and 3-methoxybenzyl chloride (5 g, 31.9 mmol). Yield 9.28 g, (99%); yellow oil; MS: 226 (M+H).

Sources & evidence

ORD record: ord-e6f217249b524f1995600e9278f0f9b8
Source dataset: uspto-grants-2001_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06331563B1

Reaction notes

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