反应详情

Experimental conditions analogous to those described for Step 4 of Example 60, from 3.15 g (9.77 mmol) of 1-(6-methyl-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester, 80 mL of 1:1 methanol-water mixture and 0.28 g (11.7 mmol) of lithium hydroxide with a work-up consisting only of thorough evaporation of solvents.

1. customconsisting only of thorough evaporation of solvents