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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270761Generated: November 1, 2026

HCID 20714641, compound → N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-(thiophene-2-carbonyl)amino-L-alanine

https://huagongshe.com/reaction/2270761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 20714641HCID 20714641—
ReactantHCID 20714643HCID 20714643—
ReactantHCID 20714644HCID 20714644—
ReactantHCID 20714645HCID 20714645—
ReactantHCID 20714646HCID 20714646—
ReactantHCID 20714659HCID 20714659—
ReactantHCID 68819182HCID 68819182—
ReactantHCID 68820442HCID 68820442—
ProductN-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-(thiophene-2-carbonyl)amino-L-alanineHCID 60115134—

Reaction Steps

3-(3-bromothiophene-2-carbonyl)amino-N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-L-alanine; 3-(5-bromothiophene-2-carbonyl)amino-N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3-chlorothiophene-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(5-chlorothiophene-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(4,5-dibromothiophene-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3-methylthiophene-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(5-methylthiophene-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(thiophene-3-carbonyl)]amino-L-alanine).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331640B1
Source datasetuspto-grants-2001_12
ORD IDord-fd85592aae9e42a48572d50aa4401143
Source noteuspto-grants-2001_12