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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270812Generated: October 31, 2026

2-Chloro-4-[1-oxo-3-(3-hydroxyphenyl)propyl]benzoic acid → 2-Chloro-4-(1-hydroxy-3-(3-hydroxyphenyl)propyl)benzoic acid

https://huagongshe.com/reaction/2270812

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-[1-oxo-3-(3-hydroxyphenyl)propyl]benzoic acidHCID 22661377—
Reactant2-Chloro-4-[1-hydroxy-3-(3-hydroxyphenyl)propyl]benzoic acid, methyl esterHCID 23560778—
Product2-Chloro-4-(1-hydroxy-3-(3-hydroxyphenyl)propyl)benzoic acidHCID 22661228—

Reaction Steps

This compound was prepared in90% yield from 2-chloro-4-[1-hydroxy-3-(3-hydroxyphenyl)propyl]benzoic acid, methyl ester (Example 19) by the procedure described for 2-chloro-4-[1-oxo-3-(3-hydroxyphenyl)propyl]benzoic acid (Example 41). The product was a racemic mixture and was not resolved.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331640B1
Source datasetuspto-grants-2001_12
ORD IDord-9fd90d3563ee4146a0927c390c5c70fc
Source noteuspto-grants-2001_12