HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 1-(3-Chloro-benzyl)-3-(6-dimethylamino-pyridine-3-carbonyl)-1H-quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 1-(3-Chloro-benzyl)-3-(6-chloro-pyridine-3-carbonyl)-1H-quinolin-4-one | HCID 57754604 | — |
| Product | 1-(3-Chloro-benzyl)-3-(6-dimethylamino-pyridine-3-carbonyl)-1H-quinolin-4-one | HCID 57754770 | — |
Reaction Steps
Experimental conditions analogous to those described for Example 141, from 151 mg (0.37 mmol) of 1-(3-chloro-benzyl)-3-(6-chloro-pyridine-3-carbonyl)-1H-quinolin-4-one and 2 mL 2 M dimethylamine solution. Yield: 127 mg of a yellow powder. LC-MSD, m/z for C24H20ClN3O2 [M+H]+=418.1, 420.1; HPLC retention time: 1.6 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-496b1a7e1216467896062fef38e18274 |
| Source note | uspto-grants-2009_07 |